Detection of Copy Number Alterations Using Single Cell Sequencing

Detection of Copy Number Alterations Using Single Cell Sequencing

Detection of genomic changes at single cell resolution is important for characterizing genetic heterogeneity and evolution in normal tissues, cancers, and microbial populations. Traditional methods for assessing genetic heterogeneity have been limited by low resolution, low sensitivity, and/or low s...

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Bibliographic Details
Main Authors:	Knouse, Kristin Ann, Hendricks, Austin A, Wu, Jie
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Published:	MyJoVE Corporation 2018
Online Access:	http://hdl.handle.net/1721.1/115000 https://orcid.org/0000-0003-0649-7428 https://orcid.org/0000-0002-0989-8115

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