Circulating CXCR5[superscript +]CXCR3[superscript +]PD-1[superscript lo] Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth
HIV-1–specific broadly neutralizing antibodies (bnAbs) typically develop in individuals with continuous high-level viral replication and increased immune activation, conditions that cannot be reproduced during prophylactic immunization. Understanding mechanisms supporting bnAb development in the abs...
Main Authors: | , , , , , , , , , , , , , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Society for Clinical Investigation
2018
|
Online Access: | http://hdl.handle.net/1721.1/115126 https://orcid.org/0000-0003-0710-7305 https://orcid.org/0000-0001-5670-8778 |