The kinetics of pre-mRNA splicing in the Drosophila genome and the influence of gene architecture

Production of most eukaryotic mRNAs requires splicing of introns from pre-mRNA. The splicing reaction requires definition of splice sites, which are initially recognized in either intron-spanning (‘intron definition’) or exon-spanning (‘exon definition’) pairs. To understand how exon and intron leng...

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מידע ביבליוגרפי
Main Authors: Henriques, Telmo, McCue, Kayla, Burkholder, Adam, Adelman, Karen, Pai, Athma A., Burge, Christopher B
מחברים אחרים: Massachusetts Institute of Technology. Department of Biological Engineering
פורמט: Article
יצא לאור: eLife Sciences Publications, Ltd 2018
גישה מקוונת:http://hdl.handle.net/1721.1/115145
https://orcid.org/0000-0002-7995-9948