Pharmacological Modulation of Noradrenergic Arousal Circuitry Disrupts Functional Connectivity of the Locus Ceruleus in Humans

State-dependent activity of locus ceruleus (LC) neurons has long suggested a role for noradrenergic modulation of arousal. However, in vivo insights into noradrenergic arousal circuitry have been constrained by the fundamental inaccessibility of the human brain for invasive studies. Functional magne...

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Bibliographic Details
Main Authors: Kucyi, Aaron, Napadow, Vitaly, Loggia, Marco L., Akeju, Oluwaseun, Song, Andrew H., Brown, Emery Neal
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Published: Society for Neuroscience 2018
Online Access:http://hdl.handle.net/1721.1/115197
https://orcid.org/0000-0001-9356-9156
https://orcid.org/0000-0003-2668-7819