HSF1-dependent and -independent regulation of the mammalian in vivo heat shock response and its impairment in Huntington's disease mouse models

HSF1-dependent and -independent regulation of the mammalian in vivo heat shock response and its impairment in Huntington's disease mouse models

The heat shock response (HSR) is a mechanism to cope with proteotoxic stress by inducing the expression of molecular chaperones and other heat shock response genes. The HSR is evolutionarily well conserved and has been widely studied in bacteria, cell lines and lower eukaryotic model organisms. Howe...

Full description

Bibliographic Details
Main Authors: Neueder, Andreas, Gipson, Theresa A., Batterton, Sophie, Lazell, Hayley J., Farshim, Pamela P., Paganetti, Paolo, Bates, Gillian P., Wasylenko, Theresa Anne, Housman, David E
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/115201
https://orcid.org/0000-0002-0524-5301
https://orcid.org/0000-0001-5016-0756

Internet

http://hdl.handle.net/1721.1/115201
https://orcid.org/0000-0002-0524-5301
https://orcid.org/0000-0001-5016-0756

Similar Items