Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

Immunotherapy using checkpoint-blocking antibodies against targets such as CTLA-4 and PD-1 can cure melanoma and non-small cell lung cancer in a subset of patients. The presence of CD8 T cells in the tumor correlates with improved survival. We show that immuno-positron emission tomography (immuno-PE...

Full description

Bibliographic Details
Main Authors: Rashidian, Mohammad, Ingram, Jessica R., Dougan, Michael, Dongre, Anushka, Whang, Katherine A., LeGall, Camille, Cragnolini, Juan J., Bierie, Brian, Gostissa, Monica, Gorman, James, Grotenbreg, Gijsbert M., Bhan, Atul, Weinberg, Robert A, Ploegh, Hidde
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Rockefeller University Press 2018
Online Access:http://hdl.handle.net/1721.1/115202
https://orcid.org/0000-0002-0895-3557
https://orcid.org/0000-0002-1090-6071

Internet

http://hdl.handle.net/1721.1/115202
https://orcid.org/0000-0002-0895-3557
https://orcid.org/0000-0002-1090-6071

Similar Items