Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells

Immunotherapy using checkpoint-blocking antibodies against targets such as CTLA-4 and PD-1 can cure melanoma and non-small cell lung cancer in a subset of patients. The presence of CD8 T cells in the tumor correlates with improved survival. We show that immuno-positron emission tomography (immuno-PE...

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Main Authors: Rashidian, Mohammad, Ingram, Jessica R., Dougan, Michael, Dongre, Anushka, Whang, Katherine A., LeGall, Camille, Cragnolini, Juan J., Bierie, Brian, Gostissa, Monica, Gorman, James, Grotenbreg, Gijsbert M., Bhan, Atul, Weinberg, Robert A, Ploegh, Hidde
其他作者: Massachusetts Institute of Technology. Department of Biology
格式: 文件
出版: Rockefeller University Press 2018
在线阅读:http://hdl.handle.net/1721.1/115202
https://orcid.org/0000-0002-0895-3557
https://orcid.org/0000-0002-1090-6071