Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition

Several cell-based therapies are under pre-clinical and clinical evaluation for the treatment of ischemic diseases. Poor survival and vascular engraftment rates of transplanted cells force them to work mainly via time-limited paracrine actions. Although several approaches, including the use of solub...

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Bibliographic Details
Main Authors: Zoldan, Janet, Besnier, Marie, Carreto, Laura, Saif, Jaimy, Fernandes, Rui, Santos, Tiago, Bernardino, Liliana, Emanueli, Costanza, Ferreira, Lino, Aday, Sezin, Langer, Robert S
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/115214
https://orcid.org/0000-0003-4396-7812
https://orcid.org/0000-0003-4255-0492