A multi-landing pad DNA integration platform for mammalian cell engineering

Engineering mammalian cell lines that stably express many transgenes requires the precise insertion of large amounts of heterologous DNA into well-characterized genomic loci, but current methods are limited. To facilitate reliable large-scale engineering of CHO cells, we identified 21 novel genomic...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Wroblewska, Liliana, Nelson, Tom, Zhang, Xin, Liu, Yan, Lowe, Alexis, Bandara, Kalpanie, Baijuraj, Swetha, Zhang, Lin, Gaydukov, Leonid A., Teague, Brian Paul, Jagtap, Kalpana P, Mamo, Selamawit W, Tseng, Wen Allen, Das, Jishnu, Summers, Nevin M, Lu, Timothy K, Weiss, Ron
अन्य लेखक: Massachusetts Institute of Technology. Department of Biological Engineering
स्वरूप: लेख
प्रकाशित: Oxford University Press 2018
ऑनलाइन पहुंच:http://hdl.handle.net/1721.1/115278
https://orcid.org/0000-0002-9833-2817
https://orcid.org/0000-0002-8244-8022
https://orcid.org/0000-0002-9999-6690
https://orcid.org/0000-0003-0396-2443