Enhancing Evolutionary Couplings with Deep Convolutional Neural Networks

Enhancing Evolutionary Couplings with Deep Convolutional Neural Networks

While genes are defined by sequence, in biological systems a protein's function is largely determined by its three-dimensional structure. Evolutionary information embedded within multiple sequence alignments provides a rich source of data for inferring structural constraints on macromolecules....

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Bibliographic Details
Main Authors: Liu, Yang, Ye, Qing, Peng, Jian, Palmedo, Peter Franklin, Berger Leighton, Bonnie
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/115385
https://orcid.org/0000-0002-2724-7228

Internet

http://hdl.handle.net/1721.1/115385
https://orcid.org/0000-0002-2724-7228

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