Structured States of Disordered Proteins from Genomic Sequences

Protein flexibility ranges from simple hinge movements to functional disorder. Around half of all human proteins contain apparently disordered regions with little 3D or functional information, and many of these proteins are associated with disease. Building on the evolutionary couplings approach pre...

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Bibliographic Details
Main Authors: Toth-Petroczy, Agnes, Ingraham, John, Hopf, Thomas A., Sander, Chris, Marks, Debora S., Palmedo, Peter Franklin, Berger Leighton, Bonnie
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/115426
https://orcid.org/0000-0002-2724-7228