Intermediate DNA methylation is a conserved signature of genome regulation

Intermediate DNA methylation is a conserved signature of genome regulation

The role of intermediate methylation states in DNA is unclear. Here, to comprehensively identify regions of intermediate methylation and their quantitative relationship with gene activity, we apply integrative and comparative epigenomics to 25 human primary cell and tissue samples. We report 18,452...

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Detalhes bibliográficos
Principais autores: Elliott, GiNell, Hong, Chibo, Xing, Xiaoyun, Zhou, Xin, Li, Daofeng, Coarfa, Cristian, Bell, Robert J.A., Maire, Cecile L., Ligon, Keith L., Sigaroudinia, Mahvash, Gascard, Philippe, Tlsty, Thea D., Harris, R. Alan, Schalkwyk, Leonard C., Bilenky, Misha, Mill, Jonathan, Farnham, Peggy J., Kellis, Manolis, Marra, Marco A., Milosavljevic, Aleksandar, Hirst, Martin, Stormo, Gary D., Wang, Ting, Costello, Joseph F.
Outros Autores: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Formato: Artigo
Publicado em: Nature Publishing Group 2018
Acesso em linha:http://hdl.handle.net/1721.1/115440

Internet

http://hdl.handle.net/1721.1/115440

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