Cellular biophysical markers of hydroxyurea treatment in sickle cell disease

Using a common-path interferometric technique, we measure biomechanical and morphological properties of individual red blood cells in SCD patients as a function of cell density, and investigate the correlation of these biophysical properties with drug intake as well as other clinically measured para...

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Bibliographic Details
Main Authors: Du, E., Papageorgiou, Dimitrios P., Higgins, John, Kato, Gregory J., Suresh, Subra, So, Peter T. C., Hosseini, Poorya, Abidi, Sabia, Dao, Ming, Yaqoob, Zahid, Park, YongKeun, Ph.D. Massachusetts Institute of Technology
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: SPIE 2018
Online Access:http://hdl.handle.net/1721.1/115510
https://orcid.org/0000-0003-4698-6488
https://orcid.org/0000-0001-7347-7887
https://orcid.org/0000-0002-7508-4320
https://orcid.org/0000-0001-5372-385X