Bruton's Tyrosine Kinase (BTK) and Vav1 Contribute to Dectin1-Dependent Phagocytosis of Candida albicans in Macrophages

Bruton's Tyrosine Kinase (BTK) and Vav1 Contribute to Dectin1-Dependent Phagocytosis of Candida albicans in Macrophages

Phagocytosis of the opportunistic fungal pathogen Candida albicans by cells of the innate immune system is vital to prevent infection. Dectin-1 is the major phagocytic receptor involved in anti-fungal immunity. We identify two new interacting proteins of Dectin-1 in macrophages, Bruton's Tyrosi...

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Bibliografiska uppgifter
Huvudupphovsmän: Strijbis, Karin, Tafesse, Fikadu G., Fairn, Gregory D., Witte, Martin D., Dougan, Stephanie K., Watson, Nicki, Spooner, Eric, Esteban, Alexandre, Vyas, Valmik K., Grinstein, Sergio, Fink, Gerald R, Ploegh, Hidde
Övriga upphovsmän: Massachusetts Institute of Technology. Department of Biology
Materialtyp: Artikel
Publicerad: Public Library of Science (PLoS) 2018
Länkar:http://hdl.handle.net/1721.1/116115
https://orcid.org/0000-0003-3704-2899
https://orcid.org/0000-0002-1090-6071

Internet

http://hdl.handle.net/1721.1/116115
https://orcid.org/0000-0003-3704-2899
https://orcid.org/0000-0002-1090-6071

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