The aneuploidy paradox: costs and benefits of an incorrect karyotype
Aneuploidy has a paradoxical effect on cell proliferation. In all normal cells analyzed to date, aneuploidy has been found to decrease the rate of cell proliferation. Yet, aneuploidy is also a hallmark of cancer, a disease of enhanced proliferative capacity, and aneuploid cells are frequently recove...
| Main Authors: | , |
|---|---|
| Outros autores: | |
| Formato: | Artigo |
| Publicado: |
Elsevier
2018
|
| Acceso en liña: | http://hdl.handle.net/1721.1/116116 https://orcid.org/0000-0003-1381-1323 https://orcid.org/0000-0001-9837-0314 |