The aneuploidy paradox: costs and benefits of an incorrect karyotype
Aneuploidy has a paradoxical effect on cell proliferation. In all normal cells analyzed to date, aneuploidy has been found to decrease the rate of cell proliferation. Yet, aneuploidy is also a hallmark of cancer, a disease of enhanced proliferative capacity, and aneuploid cells are frequently recove...
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Elsevier
2018
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| Online Access: | http://hdl.handle.net/1721.1/116116 https://orcid.org/0000-0003-1381-1323 https://orcid.org/0000-0001-9837-0314 |