Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types

Background Single-cell genomic methods now provide unprecedented resolution for characterizing the component cell types and states of tissues such as the epithelial subsets of the gastrointestinal tract. Nevertheless, functional studies of these subsets at scale require faithful in...

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Bibliographic Details
Main Authors: Szucs, Matthew J, Ammendolia, Dustin A, MacMullan, Melanie A, Rakoff-Nahoum, Seth, Mead, Benjamin Elliott, Ordovas-Montanes, Jose Manuel, Braun, Alexandra Provost, Levy, Lauren, Saluja, Prerna Bhargava, Yin, Xiaolei, Hughes, Travis K., Wadsworth, Marc Havens, Ahmad, Rushdy, Carr, Steven A, Langer, Robert S, Collins, James J., Shalek, Alexander K, Karp, Jeffrey Michael
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Biomed Central Ltd 2018
Online Access:http://hdl.handle.net/1721.1/116280
https://orcid.org/0000-0001-7258-7777
https://orcid.org/0000-0002-7941-2336
https://orcid.org/0000-0001-8624-8928
https://orcid.org/0000-0001-8291-8672
https://orcid.org/0000-0001-9376-164X
https://orcid.org/0000-0002-7203-4299
https://orcid.org/0000-0003-4255-0492
https://orcid.org/0000-0002-5560-8246
https://orcid.org/0000-0001-5670-8778

Internet

http://hdl.handle.net/1721.1/116280
https://orcid.org/0000-0001-7258-7777
https://orcid.org/0000-0002-7941-2336
https://orcid.org/0000-0001-8624-8928
https://orcid.org/0000-0001-8291-8672
https://orcid.org/0000-0001-9376-164X
https://orcid.org/0000-0002-7203-4299
https://orcid.org/0000-0003-4255-0492
https://orcid.org/0000-0002-5560-8246
https://orcid.org/0000-0001-5670-8778

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