Widespread Influence of 3′-End Structures on Mammalian mRNA Processing and Stability

The physiological relevance of structures within mammalian mRNAs has been elusive, as these mRNAs are less folded in cells than in vitro and have predicted secondary structures no more stable than those of random sequences. Here, we investigate the possibility that mRNA structures facilitate the 3′-...

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Bibliographic Details
Main Authors: Wu, Xuebing, Bartel, David P., Bartel, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Elsevier BV 2018
Online Access:http://hdl.handle.net/1721.1/116297
https://orcid.org/0000-0003-0369-5269
https://orcid.org/0000-0002-3872-2856