Impact of MicroRNA Levels, Target-Site Complementarity, and Cooperativity on Competing Endogenous RNA-Regulated Gene Expression

Impact of MicroRNA Levels, Target-Site Complementarity, and Cooperativity on Competing Endogenous RNA-Regulated Gene Expression

Expression changes of competing endogenous RNAs (ceRNAs) have been proposed to influence microRNA (miRNA) activity and thereby regulate other transcripts containing miRNA-binding sites. Here, we find that although miRNA levels define the extent of repression, they have little effect on the magnitude...

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Bibliographic Details
Main Authors: Denzler, Rémy, Title, Alexandra C., Stoffel, Markus, McGeary, Sean Edward, Agarwal, Vikram, Bartel, David
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Published: Elsevier BV 2018
Online Access:http://hdl.handle.net/1721.1/116299
https://orcid.org/0000-0001-5343-6447
https://orcid.org/0000-0001-8148-952X
https://orcid.org/0000-0002-3872-2856

Internet

http://hdl.handle.net/1721.1/116299
https://orcid.org/0000-0001-5343-6447
https://orcid.org/0000-0001-8148-952X
https://orcid.org/0000-0002-3872-2856

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