In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities

In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities

The integrity of our DNA is challenged with at least 100,000 lesions per cell on a daily basis. Failure to repair DNA damage efficiently can lead to cancer, immunodeficiency, and neurodegenerative disease. Base excision repair (BER) recognizes and repairs minimally helix-distorting DNA base lesions...

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Bibliographic Details
Main Authors: Chaim, Isaac Alexander, Nagel, Zachary D., Jordan, Jennifer, Mazzucato, Patrizia, Ngo, Le P, Samson, Leona D
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/116328
https://orcid.org/0000-0003-1787-046X
https://orcid.org/0000-0001-7455-5648
https://orcid.org/0000-0002-7112-1454

Internet

http://hdl.handle.net/1721.1/116328
https://orcid.org/0000-0003-1787-046X
https://orcid.org/0000-0001-7455-5648
https://orcid.org/0000-0002-7112-1454

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