In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities
The integrity of our DNA is challenged with at least 100,000 lesions per cell on a daily basis. Failure to repair DNA damage efficiently can lead to cancer, immunodeficiency, and neurodegenerative disease. Base excision repair (BER) recognizes and repairs minimally helix-distorting DNA base lesions...
| Main Authors: | , , , , , |
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| 格式: | 文件 |
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National Academy of Sciences (U.S.)
2018
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| 在线阅读: | http://hdl.handle.net/1721.1/116328 https://orcid.org/0000-0003-1787-046X https://orcid.org/0000-0001-7455-5648 https://orcid.org/0000-0002-7112-1454 |