Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis

The mitochondrion maintains and regulates its proteome with chaperones primarily inherited from its bacterial endosymbiont ancestor. Among these chaperones is the AAA+ unfoldase ClpX, an important regulator of prokaryotic physiology with poorly defined function in the eukaryotic mitochondrion. We ob...

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Bibliographic Details
Main Authors: Yien, Yvette Y., Huston, Nicholas C., Branco, Diana S., Hildick-Smith, Gordon J., Rhee, Kyu Y., Paw, Barry H., Kardon, Julia R., Baker, Tania
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Elsevier BV 2018
Online Access:http://hdl.handle.net/1721.1/116329
https://orcid.org/0000-0002-6621-4461