Twenty-five years of mTOR: Uncovering the link from nutrients to growth

In my PNAS Inaugural Article, I describe the development of the mTOR field, starting with efforts to understand the mechanism of action of the drug rapamycin, which ∼25 y ago led to the discovery of the mTOR protein kinase. I focus on insights that we have contributed and on work that has been parti...

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Bibliographic Details
Main Author: Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Proceedings of the National Academy of Sciences 2018
Online Access:http://hdl.handle.net/1721.1/116330
https://orcid.org/0000-0002-1446-7256