EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling
Tissue regeneration relies on adult stem cells (SCs) that possess the ability to self-renew and produce differentiating progeny. In an analogous manner, the development of certain carcinomas depends on a small subset of tumor cells, called “tumor-initiating cells” (TICs), with SC-like properties. Ma...
| Principais autores: | , , , , , |
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| Outros Autores: | |
| Formato: | Artigo |
| Publicado em: |
National Academy of Sciences (U.S.)
2018
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| Acesso em linha: | http://hdl.handle.net/1721.1/116331 https://orcid.org/0000-0003-2175-4066 https://orcid.org/0000-0002-0895-3557 https://orcid.org/0000-0001-9451-2194 |