Molecular Basis of C–N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase

Deamination of choline catalyzed by the glycyl radical enzyme choline trimethylamine-lyase (CutC) has emerged as an important route for the production of trimethylamine, a microbial metabolite associated with both human disease and biological methane production. Here, we have determined five high-re...

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Bibliographic Details
Main Authors: Bodea, Smaranda, Balskus, Emily P., Funk, Michael Andrew, Drennan, Catherine L
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Published: Elsevier BV 2018
Online Access:http://hdl.handle.net/1721.1/116406
https://orcid.org/0000-0001-5486-2755