Cutting Edge: Loss of T Cell RIAM Precludes Conjugate Formation with APC and Prevents Immune-Mediated Diabetes
Rap1-interacting adaptor molecule (RIAM) is a Rap1 effector that mediates the recruitment of talin to integrins, thereby supporting their activation. In this study, we investigated the role of RIAM in an adoptive transfer model for type I diabetes and report that RIAM expression in T cells is necess...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Published: |
American Association of Immunologists
2018
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| Online Access: | http://hdl.handle.net/1721.1/116414 https://orcid.org/0000-0003-3214-4554 |