Cancer cells exhibit clonal diversity in phenotypic plasticity

Phenotypic heterogeneity in cancers is associated with invasive progression and drug resistance. This heterogeneity arises in part from the ability of cancer cells to switch between phenotypic states, but the dynamics of this cellular plasticity remain poorly understood. Here we apply DNA barcodes t...

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Bibliographic Details
Main Authors: Mathis, Robert Austin, Sokol, Ethan Samuel, Gupta, Piyush
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: The Royal Society 2018
Online Access:http://hdl.handle.net/1721.1/116473
https://orcid.org/0000-0001-8572-4734
https://orcid.org/0000-0002-2988-0537
https://orcid.org/0000-0002-9703-1780