Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

Neural cultures derived from Huntington's disease (HD) patient-derived induced pluripotent stem cells were used for 'omics' analyses to identify mechanisms underlying neurodegeneration. RNA-seq analysis identified genes in glutamate and GABA signaling, axonal guidance and calcium infl...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: HD iPSC Consortium, Lim, Ryan G, Salazar, Lisa L, Wilton, Daniel K, King, Alvin R, Stocksdale, Jennifer T, Sharifabad, Delaram, Lau, L Alice, Stevens, Beth, Reidling, Jack C, Winokur, Sara T, Casale, Malcolm S, Thompson, Leslie M, Pardo, Mónica, Díaz-Barriga, A Gerardo García, Straccia, Marco, Sanders, Phil, Alberch, Jordi, Canals, Josep M, Kaye, Julia A, Dunlap, Mariah, Jo, Lisa, May, Hanna, Mount, Elliot, Anderson-Bergman, Cliff, Haston, Kelly, Finkbeiner, Steven, Allen, Nicholas D, Kemp, Paul J, Atwal, Ranjit Singh, Biagioli, Marta, Gusella, James F, MacDonald, Marcy E, Akimov, Sergey S, Arbez, Nicolas, Stewart, Jacqueline, Ross, Christopher A, Mattis, Virginia B, Tom, Colton M, Ornelas, Loren, Sahabian, Anais, Lenaeus, Lindsay, Mandefro, Berhan, Sareen, Dhruv, Svendsen, Clive N, Kedaigle, Amanda Joy, Wasylenko, Theresa Anne, Yildirim, Ferah, Ng, Christopher W., Milani, Pamela, Housman, David E, Fraenkel, Ernest
Бусад зохиолчид: Massachusetts Institute of Technology. Department of Biological Engineering
Формат: Өгүүллэг
Хэвлэсэн: Springer Nature 2018
Онлайн хандалт:http://hdl.handle.net/1721.1/116515
https://orcid.org/0000-0001-6156-5046
https://orcid.org/0000-0002-0524-5301
https://orcid.org/0000-0003-1381-4313
https://orcid.org/0000-0003-0250-0474
https://orcid.org/0000-0001-5016-0756
https://orcid.org/0000-0001-9249-8181

Интернэт

http://hdl.handle.net/1721.1/116515
https://orcid.org/0000-0001-6156-5046
https://orcid.org/0000-0002-0524-5301
https://orcid.org/0000-0003-1381-4313
https://orcid.org/0000-0003-0250-0474
https://orcid.org/0000-0001-5016-0756
https://orcid.org/0000-0001-9249-8181

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