Elucidation of the Roles of Tumor Integrin  1 in the Extravasation Stage of the Metastasis Cascade

Tumor integrin β1 (ITGB1) contributes to primary tumor growth and metastasis, but its specific roles in extravasation have not yet been clearly elucidated. In this study, we engineered a three-dimensional microfluidic model of the human microvasculature to recapitulate the environment wherein extrav...

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Bibliographic Details
Main Authors: Chen, Michelle B., Lamar, John, Li, Ran, Hynes, Richard O., Kamm, Roger Dale
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: American Association for Cancer Research (AACR) 2018
Online Access:http://hdl.handle.net/1721.1/116528
https://orcid.org/0000-0001-5418-5133
https://orcid.org/0000-0002-8537-8824
https://orcid.org/0000-0001-7603-8396
https://orcid.org/0000-0002-7232-304X