Modeling Tumor Clonal Evolution for Drug Combinations Design
Cancer is a clonal evolutionary process. This presents challenges for effective therapeutic intervention, given the constant selective pressure toward drug resistance. Mathematical modeling from population genetics, evolutionary dynamics, and engineering perspectives are being increasingly employed...
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| Format: | Article |
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Elsevier BV
2018
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| Online Access: | http://hdl.handle.net/1721.1/116546 https://orcid.org/0000-0003-4610-1707 https://orcid.org/0000-0002-0050-989X |