A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Cisplatin and its platinum analogs, carboplatin and oxaliplatin, are some of the most widely used cancer chemotherapeutics. Although cisplatin and carboplatin are used primarily in germ cell, breast and lung malignancies, oxaliplatin is instead used almost exclusively to treat colorectal and other g...

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Bibliographic Details
Main Authors: Murai, Junko, Pommier, Yves, Hemann, Michael T, Bruno, Peter Michael, Liu, Yunpeng, Park, Ga Young, Koch, Catherine E., Lippard, Stephen J., Hemann, Michael, Eisen, Timothy Jonas, Pritchard, Justin R.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Published: Springer Nature 2018
Online Access:http://hdl.handle.net/1721.1/116549
https://orcid.org/0000-0003-3383-0118
https://orcid.org/0000-0001-9087-4227
https://orcid.org/0000-0002-1751-7327
https://orcid.org/0000-0002-4812-4171
https://orcid.org/0000-0002-2693-4982