A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress
Cisplatin and its platinum analogs, carboplatin and oxaliplatin, are some of the most widely used cancer chemotherapeutics. Although cisplatin and carboplatin are used primarily in germ cell, breast and lung malignancies, oxaliplatin is instead used almost exclusively to treat colorectal and other g...
Main Authors: | Murai, Junko, Pommier, Yves, Hemann, Michael T, Bruno, Peter Michael, Liu, Yunpeng, Park, Ga Young, Koch, Catherine E., Lippard, Stephen J., Hemann, Michael, Eisen, Timothy Jonas, Pritchard, Justin R. |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Published: |
Springer Nature
2018
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Online Access: | http://hdl.handle.net/1721.1/116549 https://orcid.org/0000-0003-3383-0118 https://orcid.org/0000-0001-9087-4227 https://orcid.org/0000-0002-1751-7327 https://orcid.org/0000-0002-4812-4171 https://orcid.org/0000-0002-2693-4982 |
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