Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6

Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6

The diversity of mesenchymal cell types in the lung that influence epithelial homeostasis and regeneration is poorly defined. We used genetic lineage tracing, single-cell RNA sequencing, and organoid culture approaches to show that Lgr5 and Lgr6, well-known markers of stem cells in epithelial tissue...

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Bibliographic Details
Main Authors: Lee, Joo-Hyeon, Hofree, Matan, Choi, Jinwook, Han, Seungmin, Paschini, Margherita, Bhang, Dong Ha, Kim, Carla F., Tammela, Tuomas, Marjanovic, Nemanja, Canner, David Allen, Wu, Katherine, Jacks, Tyler E., Regev, Aviv
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Elsevier BV 2018
Online Access:http://hdl.handle.net/1721.1/116555
https://orcid.org/0000-0003-3675-6961
https://orcid.org/0000-0002-0060-7131
https://orcid.org/0000-0001-5785-8911
https://orcid.org/0000-0001-8567-2049

Internet

http://hdl.handle.net/1721.1/116555
https://orcid.org/0000-0003-3675-6961
https://orcid.org/0000-0002-0060-7131
https://orcid.org/0000-0001-5785-8911
https://orcid.org/0000-0001-8567-2049

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