A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma

A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma

The heterogeneity of cellular states in cancer has been linked to drug resistance, cancer progression and the presence of cancer cells with properties of normal tissue stem cells. Secreted Wnt signals maintain stem cells in various epithelial tissues, including in lung development and regeneration....

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Bibliographic Details
Main Authors: Katajisto, Pekka, Tammela, Tuomas, Cetinbas, Naniye, Wu, Katherine, Helenius, Katja Piritta, Park, Yoona K, Azimi, Roxana S., Kerper, Natanya R., Wesselhoeft IV, Robert Alexander, Gu, Xin, Schmidt, Leah Marie, Cornwall-Brady, Milton R., Yilmaz, Omer, Xue, Wen, Bhutkar, Arjun, Jacks, Tyler E, Sanchez-Rivera, Francisco Jav, Joshi, Nik
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/116606
https://orcid.org/0000-0003-3675-6961
https://orcid.org/0000-0002-7045-7837
https://orcid.org/0000-0001-8031-0006
https://orcid.org/0000-0003-4617-8157
https://orcid.org/0000-0002-3393-6927
https://orcid.org/0000-0001-9076-8475
https://orcid.org/0000-0002-7577-4612
https://orcid.org/0000-0001-5785-8911

Internet

http://hdl.handle.net/1721.1/116606
https://orcid.org/0000-0003-3675-6961
https://orcid.org/0000-0002-7045-7837
https://orcid.org/0000-0001-8031-0006
https://orcid.org/0000-0003-4617-8157
https://orcid.org/0000-0002-3393-6927
https://orcid.org/0000-0001-9076-8475
https://orcid.org/0000-0002-7577-4612
https://orcid.org/0000-0001-5785-8911

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