A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma

The heterogeneity of cellular states in cancer has been linked to drug resistance, cancer progression and the presence of cancer cells with properties of normal tissue stem cells. Secreted Wnt signals maintain stem cells in various epithelial tissues, including in lung development and regeneration....

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Main Authors: Katajisto, Pekka, Tammela, Tuomas, Cetinbas, Naniye, Wu, Katherine, Helenius, Katja Piritta, Park, Yoona K, Azimi, Roxana S., Kerper, Natanya R., Wesselhoeft IV, Robert Alexander, Gu, Xin, Schmidt, Leah Marie, Cornwall-Brady, Milton R., Yilmaz, Omer, Xue, Wen, Bhutkar, Arjun, Jacks, Tyler E, Sanchez-Rivera, Francisco Jav, Joshi, Nik
其他作者: Koch Institute for Integrative Cancer Research at MIT
格式: 文件
出版: Nature Publishing Group 2018
在线阅读:http://hdl.handle.net/1721.1/116606
https://orcid.org/0000-0003-3675-6961
https://orcid.org/0000-0002-7045-7837
https://orcid.org/0000-0001-8031-0006
https://orcid.org/0000-0003-4617-8157
https://orcid.org/0000-0002-3393-6927
https://orcid.org/0000-0001-9076-8475
https://orcid.org/0000-0002-7577-4612
https://orcid.org/0000-0001-5785-8911