Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

Glioblastoma is a universally lethal cancer with a median survival time of approximately 15 months. Despite substantial efforts to define druggable targets, there are no therapeutic options that notably extend the lifespan of patients with glioblastoma. While previous work has largely focused on in...

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Bibliographic Details
Main Authors: Miller, Tyler E., Liau, Brian B., Wallace, Lisa C., Morton, Andrew R., Xie, Qi, Dixit, Deobrat, Factor, Daniel C., Kim, Leo J. Y., Morrow, James J., Wu, Qiulian, Mack, Stephen C., Hubert, Christopher G., Gillespie, Shawn M., Flavahan, William A., Hoffmann, Thomas, Thummalapalli, Rohit, Paddison, Patrick J., Horbinski, Craig M., Zuber, Johannes, Scacheri, Peter C., Bernstein, Bradley E., Tesar, Paul J., Rich, Jeremy N., Hemann, Michael
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Springer Nature 2018
Online Access:http://hdl.handle.net/1721.1/116638

Internet

http://hdl.handle.net/1721.1/116638

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