Enriching Peptide Libraries for Binding Affinity and Specificity Through Computationally Directed Library Design

Peptide reagents with high affinity or specificity for their target protein interaction partner are of utility for many important applications. Optimization of peptide binding by screening large libraries is a proven and powerful approach. Libraries designed to be enriched in peptide sequences that...

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Bibliographic Details
Main Authors: Chen, T. Scott, Richman, Daniel, Foight, Glenna W., Keating, Amy E.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Humana Press 2018
Online Access:http://hdl.handle.net/1721.1/116640
https://orcid.org/0000-0003-3749-7092
https://orcid.org/0000-0003-4074-8980