Enriching Peptide Libraries for Binding Affinity and Specificity Through Computationally Directed Library Design
Peptide reagents with high affinity or specificity for their target protein interaction partner are of utility for many important applications. Optimization of peptide binding by screening large libraries is a proven and powerful approach. Libraries designed to be enriched in peptide sequences that...
Main Authors: | Chen, T. Scott, Richman, Daniel, Foight, Glenna W., Keating, Amy E. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Published: |
Humana Press
2018
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Online Access: | http://hdl.handle.net/1721.1/116640 https://orcid.org/0000-0003-3749-7092 https://orcid.org/0000-0003-4074-8980 |
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