Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles
Using a diverse collection of small molecules generated from a variety of sources, we measured protein-binding activities of each individual compound against each of 100 diverse (sequence-unrelated) proteins using small-molecule microarrays. We also analyzed structural features, including complexity...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Published: |
Proceedings of the National Academy of Sciences
2018
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| Online Access: | http://hdl.handle.net/1721.1/116671 https://orcid.org/0000-0002-3772-8156 |