Mouse ooplasm confers context-specific reprogramming capacity

Enucleated oocytes have the distinctive ability to reprogram somatic nuclei back to totipotency. Here, we investigate genome-scale DNA methylation patterns after nuclear transfer and compare them to the dynamics at fertilization. We identify specific targets for DNA demethylation after nuclear trans...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Chan, Michelle M, Smith, Zachary D, Egli, Dieter, Regev, Aviv, Meissner, Alexander, Chan, Michelle Mei Wah
מחברים אחרים: Massachusetts Institute of Technology. Computational and Systems Biology Program
פורמט: Article
יצא לאור: Nature Publishing Group 2018
גישה מקוונת:http://hdl.handle.net/1721.1/116756
https://orcid.org/0000-0001-8567-2049