Loss of hepatic DEPTOR alters the metabolic transition to fasting

Loss of hepatic DEPTOR alters the metabolic transition to fasting

Objective The mechanistic target of rapamycin (mTOR) is a serine/threonine kinase that functions into distinct protein complexes (mTORC1 and mTORC2) that regulates growth and metabolism. DEP-domain containing mTOR-interacting protein (DEPTOR) is part of these complexes and is known to reduce their a...

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Bibliographic Details
Main Authors: Caron, Alexandre, Mouchiroud, Mathilde, Gautier, Nicolas, Labbé, Sébastien M., Villot, Romain, Turcotte, Laurie, Secco, Blandine, Lamoureux, Guillaume, Shum, Michael, Gélinas, Yves, Marette, André, Richard, Denis, Laplante, Mathieu, Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Elsevier BV 2018
Online Access:http://hdl.handle.net/1721.1/116771
https://orcid.org/0000-0002-1446-7256

Internet

http://hdl.handle.net/1721.1/116771
https://orcid.org/0000-0002-1446-7256

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