Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism
Mitochondria house metabolic pathways that impact most aspects of cellular physiology. While metabolite profiling by mass spectrometry is widely applied at the whole-cell level, it is not routinely possible to measure the concentrations of small molecules in mammalian organelles. We describe a metho...
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Format: | Article |
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Elsevier
2018
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Online Access: | http://hdl.handle.net/1721.1/116785 https://orcid.org/0000-0002-7043-5013 https://orcid.org/0000-0002-4227-5163 https://orcid.org/0000-0002-1446-7256 |