Landscape of X chromosome inactivation across human tissues

Landscape of X chromosome inactivation across human tissues

X chromosome inactivation (XCI) silences transcription from one of the two X chromosomes in female mammalian cells to balance expression dosage between XX females and XY males. XCI is, however, incomplete in humans: up to one-third of X-chromosomal genes are expressed from both the active and inacti...

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Bibliographic Details
Main Authors: Tukiainen, Taru, Villani, Alexandra-Chloé, Rivas, Manuel A., Marshall, Jamie L., Satija, Rahul, Aguirre, Matt, Gauthier, Laura, Fleharty, Mark, Kirby, Andrew, Cummings, Beryl B., Castel, Stephane E., Karczewski, Konrad J., Aguet, François, Byrnes, Andrea, Ardlie, Kristin G., Gelfand, Ellen T., Getz, Gad, Hadley, Kane, Handsaker, Robert E., Huang, Katherine H., Kashin, Seva, Lek, Monkol, Li, Xiao, MacArthur, Daniel G., Yen, Angela, Regev, Aviv
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Published: Springer Nature 2018
Online Access:http://hdl.handle.net/1721.1/116808
https://orcid.org/0000-0001-5951-9358
https://orcid.org/0000-0001-8567-2049

Internet

http://hdl.handle.net/1721.1/116808
https://orcid.org/0000-0001-5951-9358
https://orcid.org/0000-0001-8567-2049

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