Landscape of X chromosome inactivation across human tissues
X chromosome inactivation (XCI) silences transcription from one of the two X chromosomes in female mammalian cells to balance expression dosage between XX females and XY males. XCI is, however, incomplete in humans: up to one-third of X-chromosomal genes are expressed from both the active and inacti...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
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Springer Nature
2018
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Online Access: | http://hdl.handle.net/1721.1/116808 https://orcid.org/0000-0001-5951-9358 https://orcid.org/0000-0001-8567-2049 |