A Phase Separation Model for Transcriptional Control
Phase-separated multi-molecular assemblies provide a general regulatory mechanism to compartmentalize biochemical reactions within cells. We propose that a phase separation model explains established and recently described features of transcriptional control. These features include the formation of...
Main Authors: | Hnisz, Denes, Young, Richard A., Chakraborty, Arup K., Sharp, Phillip A., Shrinivas, Krishna,Ph. D.Massachusetts Institute of Technology. |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Published: |
Elsevier
2018
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Online Access: | http://hdl.handle.net/1721.1/116858 https://orcid.org/0000-0002-4167-9385 https://orcid.org/0000-0001-8855-8647 https://orcid.org/0000-0003-1268-9602 https://orcid.org/0000-0003-1465-1691 |
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