BROCKMAN: deciphering variance in epigenomic regulators by k-mer factorization

Background: Variation in chromatin organization across single cells can help shed important light on the mechanisms controlling gene expression, but scale, noise, and sparsity pose significant challenges for interpretation of single cell chromatin data. Here, we develop BROCKMAN (Brockman Representa...

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Bibliographic Details
Main Authors: de Boer, Carl G., Regev, Aviv
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: BioMed Central 2018
Online Access:http://hdl.handle.net/1721.1/116880
https://orcid.org/0000-0001-8567-2049