Metabolic requirements for cancer cell proliferation

Background: The study of cancer metabolism has been largely dedicated to exploring the hypothesis that oncogenic transformation rewires cellular metabolism to sustain elevated rates of growth and division. Intense examination of tumors and cancer cell lines has confirmed that many cancer-associated...

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Bibliographic Details
Main Authors: Iliopoulos, Othon, Keibler, Mark Andrew, Wasylenko, Thomas Michael, Vander Heiden, Matthew G., Stephanopoulos, Gregory, Kelleher, Joanne Keene
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: BioMed Central Ltd 2018
Online Access:http://hdl.handle.net/1721.1/116916
https://orcid.org/0000-0002-5410-6543
https://orcid.org/0000-0002-8676-5738
https://orcid.org/0000-0002-6702-4192
https://orcid.org/0000-0001-6909-4568