The Outgrowth of Micrometastases Is Enabled by the Formation of Filopodium-like Protrusions

Disseminated cancer cells that have extravasated into the tissue parenchyma must interact productively with its extracellular matrix components to survive, proliferate, and form macroscopic metastases. The biochemical and cell biologic mechanisms enabling this interaction remain poorly understood. W...

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Bibliographic Details
Main Authors: Shibue, Tsukasa, Brooks, Mary W., Inan, M. Fatih, Reinhardt, Ferenc, Weinberg, Robert A
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: American Association for Cancer Research (AACR) 2018
Online Access:http://hdl.handle.net/1721.1/116963
https://orcid.org/0000-0002-0895-3557