Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability

The epithelial-to-mesenchymal transition enables carcinoma cells to acquire malignancy-associated traits and the properties of tumor-initiating cells (TICs). TICs have emerged in recent years as important targets for cancer therapy, owing to their ability to drive clinical relapse and enable metasta...

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Bibliographic Details
Main Authors: Pattabiraman, D. R., Bierie, B., Kober, K. I., Thiru, P., Krall, J. A., Zill, C., Reinhardt, F., Tam, W. L.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: American Association for the Advancement of Science (AAAS) 2018
Online Access:http://hdl.handle.net/1721.1/116976

Internet

http://hdl.handle.net/1721.1/116976

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