Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability
The epithelial-to-mesenchymal transition enables carcinoma cells to acquire malignancy-associated traits and the properties of tumor-initiating cells (TICs). TICs have emerged in recent years as important targets for cancer therapy, owing to their ability to drive clinical relapse and enable metasta...
| Main Authors: | , , , , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Published: |
American Association for the Advancement of Science (AAAS)
2018
|
| Online Access: | http://hdl.handle.net/1721.1/116976 |