Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control
Understanding how transcriptional enhancers control over 20,000 protein-coding genes to maintain cell-type-specific gene expression programs in all human cells is a fundamental challenge in regulatory biology. Recent studies suggest that gene regulatory elements and their target genes generally occu...
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Formato: | Artigo |
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Elsevier
2018
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Acesso em linha: | http://hdl.handle.net/1721.1/116984 https://orcid.org/0000-0001-8855-8647 |