Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes
Most human genes are loaded with promoter-proximally paused RNA polymerase II (Pol II) molecules that are poised for release into productive elongation by P-TEFb. We present evidence that Gdown1, the product of the POLR2M gene that renders Pol II responsive to Mediator, is involved in Pol II elongat...
Үндсэн зохиолчид: | , , , , , , , , , , , |
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Бусад зохиолчид: | |
Формат: | Өгүүллэг |
Хэвлэсэн: |
Elsevier
2018
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Онлайн хандалт: | http://hdl.handle.net/1721.1/116987 https://orcid.org/0000-0001-8855-8647 |