Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes
Most human genes are loaded with promoter-proximally paused RNA polymerase II (Pol II) molecules that are poised for release into productive elongation by P-TEFb. We present evidence that Gdown1, the product of the POLR2M gene that renders Pol II responsive to Mediator, is involved in Pol II elongat...
| Үндсэн зохиолчид: | , , , , , , , , , , , |
|---|---|
| Бусад зохиолчид: | |
| Формат: | Өгүүллэг |
| Хэвлэсэн: |
Elsevier
2018
|
| Онлайн хандалт: | http://hdl.handle.net/1721.1/116987 https://orcid.org/0000-0001-8855-8647 |