Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes

Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes

Most human genes are loaded with promoter-proximally paused RNA polymerase II (Pol II) molecules that are poised for release into productive elongation by P-TEFb. We present evidence that Gdown1, the product of the POLR2M gene that renders Pol II responsive to Mediator, is involved in Pol II elongat...

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Bibliographic Details
Main Authors: Cheng, Bo, Li, Tiandao, Rahl, Peter B., Adamson, Todd E., Loudas, Nicholas B., Guo, Jiannan, Varzavand, Katayoun, Cooper, Jeffrey J., Hu, Xiaopeng, Gnatt, Averell, Price, David H., Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/116987
https://orcid.org/0000-0001-8855-8647

Internet

http://hdl.handle.net/1721.1/116987
https://orcid.org/0000-0001-8855-8647

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