The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells

The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells

Invariant natural killer T cells (iNKT cells) are innate-like lymphocytes that protect against infection, autoimmune disease and cancer. However, little is known about the epigenetic regulation of iNKT cell development. Here we found that the H3K27me3 histone demethylase UTX was an essential cell-in...

Full description

Bibliographic Details
Main Authors: Beyaz, Semir, Kim, Ji Hyung, Pinello, Luca, Huang, Jialiang, Kerenyi, Marc A, Das, Partha P, Barnitz, R Anthony, Herault, Aurelie, Haining, W Nicholas, Passegue, Emmanuelle, Yuan, Guo-Cheng, Orkin, Stuart H, Winau, Florian, Xifaras, Michael, Dogum, Rizkullah, Yilmaz, Omer, Hu, Yu,M.C.P.Massachusetts Institute of Technology.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Springer Nature 2018
Online Access:http://hdl.handle.net/1721.1/117007
https://orcid.org/0000-0002-7577-4612

Internet

http://hdl.handle.net/1721.1/117007
https://orcid.org/0000-0002-7577-4612

Similar Items