Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism

Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism

Transcriptional dysregulation of the MYC oncogene is among the most frequent events in aggressive tumor cells, and this is generally accomplished by acquisition of a super-enhancer somewhere within the 2.8 Mb TAD where MYC resides. We find that these diverse cancer-specific super-enhancers, differin...

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Bibliographic Details
Main Authors: Schuijers, Jurian, Day, Daniel Sindt, Hnisz, Denes, Lee, Tong Ihn, Manteiga, John Colonnese, Weintraub, Abraham Selby, Zamudio Montes de Oca, Alicia, Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/117042
https://orcid.org/0000-0002-0385-6176
https://orcid.org/0000-0003-0998-9882
https://orcid.org/0000-0001-6263-2423
https://orcid.org/0000-0001-8855-8647

Internet

http://hdl.handle.net/1721.1/117042
https://orcid.org/0000-0002-0385-6176
https://orcid.org/0000-0003-0998-9882
https://orcid.org/0000-0001-6263-2423
https://orcid.org/0000-0001-8855-8647

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